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PhyloGenes is a web resource that displays pre-computed phylogenetic trees of gene families alongside experimental gene function data to facilitate inference of unknown gene function in plants.


PhyloGenes is managed by the nonprofit Phoenix Bioinformatics Corporation. It is co-developed by Phoenix Bioinformatics and the PANTHER project at University of Southern California, and is supported by funding provided by the National Science Foundation (Grant No. DBI-1661543).


Citing PhyloGenes: 

PhyloGenes: An online phylogenetics and functional genomics resource for plant gene function inference 

Zhang P, Berardini TZ, Ebert D, Li Q, Mi H, Muruganujan A, Prithvi T, Reiser L, Sawant S, Thomas PD, Huala E

Plant Direct. 2020 Dec;4(12):e00293


Current release (version 2.2)

December 4, 2020. We are pleased to announce the PhyloGenes version 2.2 release.  The gene families and gene trees are from the  PANTHER 15.0 release. In PhyloGenes only  genes from plant genomes and selected non-plant model organisms were included. Genes from other genomes in the PANTHER build have been removed (pruned). More stats

Experimental gene function data was extracted from the Gene Ontology Consortium (files created on 2020-04-28). Phylogenetic inferred gene function data was extracted from the PAINT project (files created on 2020-05-21).


What’s new:

  • You can download the multiple sequence alignment of a gene family. This feature is accessed from the Operations menu icon above a gene tree.
  • Click on a gene, a leaf node on a gene tree, you will be able to download a list of its plant orthologs. More...   


Please take a few minutes to share with us your experience of using the PhyloGenes resource. 


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